%0 Journal Article %J Nat. Nanotechnol. %D 2015 %T

Nanoscale NMR spectroscopy and imaging of multiple nuclear species

%A DeVience, Stephen J. %A Pham, Linh M. %A Lovchinsky, Igor %A Sushkov, Alexander O. %A Nir Bar-Gill %A Belthangady, Chinmay %A Casola, Francesco %A Corbett, Madeleine %A Zhang, Huiliang %A Lukin, Mikhail %A Park, Hongkun %A Yacoby, Amir %A Walsworth, Ronald L. %X

Nuclear magnetic resonance (NMR) spectroscopy and magnetic resonance imaging (MRI) provide non-invasive information about multiple nuclear species in bulk matter, with wide-ranging applications from basic physics and chemistry to biomedical imaging. However, the spatial resolution of conventional NMR and MRI is limited to several micrometres even at large magnetic fields (>1 T), which is inadequate for many frontier scientific applications such as single-molecule NMR spectroscopy and in vivo MRI of individual biological cells. A promising approach for nanoscale NMR and MRI exploits optical measurements of nitrogen–vacancy (NV) colour centres in diamond, which provide a combination of magnetic field sensitivity and nanoscale spatial resolution unmatched by any existing technology, while operating under ambient conditions in a robust, solid-state system. Recently, single, shallow NV centres were used to demonstrate NMR of nanoscale ensembles of proton spins, consisting of a statistical polarization equivalent to ∼100–1,000 spins in uniform samples covering the surface of a bulk diamond chip. Here, we realize nanoscale NMR spectroscopy and MRI of multiple nuclear species (1H, 19F, 31P) in non-uniform (spatially structured) samples under ambient conditions and at moderate magnetic fields (∼20 mT) using two complementary sensor modalities.

%B Nat. Nanotechnol. %I Nature Publishing Group %V 10 %P 129-134 %G eng %U http://dx.doi.org/10.1038/nnano.2014.313 %N 2 %R 10.1038/nnano.2014.313